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    Structural Biology And Drug Discovery Services

SARomics Biostructures’ state of the art platform is built on many years of extensive expertise and experience in the fields of protein crystallization, X-ray crystallography and protein NMR spectroscopy. We offer a broad range of services which cover all aspects of structural biology:

• Gene-to-structure, FastLaneTM Standard & FastLaneTM Premium structures
• Protein NMR spectroscopy
• Protein expression, purification & crystallization
• Biophysical methods for protein characterization
• A catalogue of high purity crystallization grade recombinant proteins

The SARomics Biostructures team has also gathered many years of experience in biophysical characterization, crystallization and structure determination of antibody:antigen complexes. By combining NMR spectroscopy and X-ray crystallography, we can provide detailed characterization of biosimilars high order structure (HOS), including an analysis of its comparability with the originator antibody.
Please follow the links below for details of the services.

NEWS


January 2020
The new Protein Shop: A
catalogue of recombinant proteins are now offered to our customers…

Visit our blog to view additional company news!

Structural Biology Services

  • FastLaneTM Premium

  • FastLaneTM Standard

  • Gene-to-Structure

  • Industrial Enzymes

  • NMR Spectroscopy

  • Recombinant Proteins

  • Antibody-Antigen Complex Structure

  • Biosimilars Structure Characterization

  • ProPHECY™ Protein Optimization

Fragment-Based Drug Discovery

SARomics Biostructures’ integrated drug discovery services platform, which is run in close cooperation with Red Glead Discovery, combines key capabilities from a number of disciplines, which include:

• Weak Affinity Chromatography (WAC™)
• Nuclear Magnetic Resonance spectroscopy (NMR)
• Thermal Shift Assay (DSF)
• Computational chemistry
• Biochemical & cell-based screening

Our proprietary weak affinity chromatography-based hit identification method has a proven track record of providing high quality lead fragments in projects which had often failed earlier screening efforts. The platform offers a variety of both pre-determined and custom drug discovery service packages.

Drug Discovery Services

  • Weak-Affinity Chromatography

  • Fragment-Based Lead Generation

  • Structure-Based Drug Design

  • In Silico Lead Discovery