Synchrotron X-ray Crystallography in Drug Discovery
We highlight a study conducted by the AstraZeneca team on synchrotron X-ray crystallography in drug discovery (Käck & Sjögren, 2024).
publications
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2023 – New Publications & Collaborations
In this article, we will discuss some significant publications and company activities in 2023. The publications showcase our expertise in the three main areas of our services: X-ray crystallography, NMR spectroscopy, and integrated drug discovery.
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Protein-Ligand Interactions: Room Temperature or Cryo-Crystallography?
After many years of cryo-crystallography dominance, room-temperature X-ray crystallography using synchrotron radiation has returned. We discuss the application of room-temperature X-ray crystallography in drug design.
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The Dusquetide Saga – a Structural Blast From the Past!
A pleasant surprise! A paper describing the interaction of the therapeutic peptide dusquetide with the ZZ domain of the autophagic receptor p62 was published around 12 years after the structure was solved!
