• Fragment library - Proprietary library design for easy hit expansion, specifically ordered sets and client libraries. Please enquire for details.
• WAC™ screening technology - Our proprietary weak affinity chromatography (WAC™) screening technology allows simultaneous identification of weak binders (mM-μM) in complex mixtures, as well as Kd calculation. Offers include Pilot screen, Fragment screen and Ligandability screen.
• Biophysical screening - Efficient hit identification using thermal-shift assay (DSF), isothermal titration calorimetry (ITC), Microscale thermophoresis (MST), NMR spectroscopy and X-ray crystallography.
• Computational chemistry - Library design, hit expansion, pharmacophore- and shape-based virtual screening, scaffold hopping, QSAR analysis and optimization.
• Structural biology - Highly efficient structural biology platform with proprietary high-throughput crystallization and structure determination protocols.
• Medicinal chemistry - Through our collaboration with Red Glead we offer expertise in lead optimization, biological characterization, medicinal chemistry and ADME.
FOR DETAILS PLEASE SCROL DOWN!