SARomics protein crystallization and crystallography services

Contract Protein Crystallography Services: FastLaneā„¢ Premium Library

SARomics Biostructures FastLane Premium library of verified drug target protein structures (off-the-shelf structures) offers contract crystallization and X-ray structure determination services of ligand-protein complexes with turnaround time of 2 to 8 weeks. The library offers three-dimensional crystallographic structures of kinases, phosphatases, epigenetic targets and other proteins.

“Off-the-shelf“ means that we have direct experience of crystallization of all the proteins in the list and that we have a protein sample stored in our lab ready for crystallization - no time-consuming protein expression and purification is required and the project can start immediately upon arrival of customer’s compounds. The majority of these proteins have also been crystallized at the company in complex with ligands. The list of available proteins can be viewed below.

If you don’t find the structure of you target please
contact us, we may still have it but have not posted it yet to this page. Our services also include FastLane™ Standard library of structures and Gene-to-Structure services.

Please note that all proteins in the list (crystallization-grade purity) may also be purchased, e.g. for assays and other purposes.

Please scroll down to see the entire list of available FastLane™ Premium X-ray structures

AR or Aldose reductase (a.a. 1-316)
ATAD2A - Bromodomain, ATPase family AAA domain-containing protein 2 (a.a. 981-1108)
ATAD2B - Bromodomain, ATPase family AAA domain-containing protein 2B, (a.a. 952-1086)

BCAT2 - Branched-chain-amino-acid aminotransferase, mitochondrial
Beta-lactamase - BlaC or Beta-lactamase (M. tuberculosis)
Bfl-1 - Bcl-2-related protein A1
BTK kinase - Tyrosine-protein kinase BTK

Cathepsin C - DPPI or Dipeptidyl peptidase 1
CLK3 - Dual specificity protein kinase CLK3
CK2 kinase - Casein kinase II subunit alpha

DAPK3 kinase - Death-associated protein kinase 3
DHODH - Dihydroorotate dehydrogenase (human)
DPP4 - Dipeptidyl peptidase 4

EphA7 kinase - Ephrin type-A receptor 7

Gal-3C - Galectin-3 carbohydrate recognition domain
GMPR2 - GMP reductase 2

HSP90 - Heat shock protein HSP 90-alpha
HER2 - Receptor tyrosine-protein kinase erbB-2

IL-17A - Interleukin-17A
IL-23 - Interleukin-23

JMJD2C - KDM4C or Lysine-specific demethylase 4C (a.a. 1-347)

LDHA - L-lactate dehydrogenase A chain (rabbit)

MAP2K4 - Dual specificity mitogen-activated protein kinase kinase 4

PIP4K2A kinase - Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
PDE4D - cAMP-specific 3',5'-cyclic phosphodiesterase 4D
PFKFB3 - 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
PLK4 kinase - Serine/threonine-protein kinase
PTP1B - PTPN1 or Tyrosine-protein phosphatase non-receptor type 1

ROR-gamma - Nuclear receptor ROR-gamma

S100A4 - Mts1 or Protein S100-A4
S100A9 - MRP14 or Protein S100-A9
S100A12 - Protein S100-A12
SMARCA2 - bromodomain of human BRM
SMARCA4 - Transcription activator BRG1
STK10 kinase - LOK or Serine/threonine-protein kinase 10
STK17B kinase - DRAK2 or Serine/threonine-protein kinase 17B

Thrombin - human alpha thrombin
TIM3 - Hepatitis A virus cellular receptor 2
TNF-alpha - Tumor necrosis factor

USP7 - Ubiquitin carboxyl-terminal hydrolase 7 ((a.a. 208-554)
USP8 - Ubiquitin carboxyl-terminal hydrolase 8

Vps34 - Phosphatidylinositol 3-kinase catalytic subunit type 3

PFKFB3 3D structure
Cathepsin C 3D structure
ATAD2 Bromodomain 3D structure
Aldose reductase 3D structure
PDE4D2 3D structure
M. tuberculosis beta-lactamase (BlaC) 3D structure
M. tuberculosis beta-lactamase (BlaC) 3D structure
M. tuberculosis beta-lactamase (BlaC) 3D structure