synchrotron X-ray Crystallography in drug Discovery
We highlight a study conducted by the AstraZeneca team on synchrotron X-ray crystallography in drug discovery (Käck & Sjögren, 2024).
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Crystallographic Fragment Screening In Drug Discovery: Background & Advantages
Technical developments have made crystallographic fragment screening the most effective method for screening fragment libraries. Here, we provide a brief overview of the method and its requirements.
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The Exciting World of Macrocycle Structures
In this post, we discuss the unique structure of macrocyclic peptide drugs (often 4 to 24 amino acids), which falls between small-molecule drugs and biologics (such as monoclonal antibodies).
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Early Drug Discovery Services: What Does CRO outsourcing Offer?
We discuss the the early drug discovery services market and highlight the integrated drug discovery CRO services provided by SARomics Biostructures.
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How was our 2024?
It was a year marked by the most significant changes in recent memory: a new home for the company, four new team members, new collaborations, new publications, a revamped homepage, and a greatly expanded list of off-the-shelf structures.
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DNA-Encoded Library Screening For Drug Discovery
SARomics Biostructures AB and Vipergen ApS partner to offer hit and lead identification services based on Vipergen’s unique DNA-encoded library (DEL) screening technology.
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NMR Spectroscopy in Comparative Higher Order Structure Analysis
In the this article we discuss evidence that shows that NMR spectroscopy is far superior to other established methods for biosimilar’s higher order structure analysis.
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WAC™ Fragment screening technology: Principles & Advantages
In this article, we discuss weak affinity chromatography (WAC™), the proprietary fragment screening technique jointly owned by SARomics Biostructures and Red Glead Discovery.
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2023 – New Publications & Collaborations
In this article, we will discuss some significant publications and company activities in 2023. The publications showcase our expertise in the three main areas of our services: X-ray crystallography, NMR spectroscopy, and integrated drug discovery.
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X-ray Crystallography at Room-Temperature: There are Advamtages!
After many years of cryo-crystallography dominance, room-temperature X-ray crystallography using synchrotron radiation has returned. We discuss the application of room-temperature X-ray crystallography in drug design.
