Planning your experiment: Details of the technology
An outline of details of the experimental procedures will help you in the design of your experiments:
Protein X-ray crystallography
Read more here »
Structure-based drug design
Read more here »
NMR spectroscopy
Read more here »
Protein homology modelling
Read more here »
Peptide & biomolecule optimization
Read more here »
Protein X-ray crystallography
Read more here »
Structure-based drug design
Read more here »
NMR spectroscopy
Read more here »
Protein homology modelling
Read more here »
Peptide & biomolecule optimization
Read more here »
When contacting us:
For a general inquiry it is helpful to provide us with the following details:
• X-ray crystallographic and NMR structure determination: Approximate molecular weight of the protein; is their a known structure of the protein in the PDB; are you going to provide the material or do you expect us to clone, express and purify the protein for you; in case you would like us to determine a structure of a complex, it would also be helpful to provide a binding constant for the complex, if available.
• For small-angle X-ray scattering (SAXS) services, please let us know the aim of the study: For example, do you need information on the state of your protein in solution (the oligomerization state, presence of aggregates, etc); are you interested in the overall shape of your protein or complex; are you interested in some conformational changes due to ligand binding, etc.
For a general inquiry it is helpful to provide us with the following details:
• X-ray crystallographic and NMR structure determination: Approximate molecular weight of the protein; is their a known structure of the protein in the PDB; are you going to provide the material or do you expect us to clone, express and purify the protein for you; in case you would like us to determine a structure of a complex, it would also be helpful to provide a binding constant for the complex, if available.
• For small-angle X-ray scattering (SAXS) services, please let us know the aim of the study: For example, do you need information on the state of your protein in solution (the oligomerization state, presence of aggregates, etc); are you interested in the overall shape of your protein or complex; are you interested in some conformational changes due to ligand binding, etc.