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Protein Crystallography Services

We provide a broad range of custom crystallography services for outsourcing structural biology and structure-based drug design projects. Our structural services include:

•
Gene-to-Structure: Expression, purification, crystallization and structure determination of proteins of known structure
• De novo protein structure determination
• Protein-ligand co-crystallization and structure determination
• Single-crystal X-ray data collection (customer’s crystals)
• Protein characterization
•
Off-the-shelf structures

For kinase-related services please visit our KINOMED page. For the details and requirements of the experimental procedures please check our technology help pages.


Low volume high-throughput custom protein crystallization services

SARomics Biostructures runs a state-of-the art Cassiopeia protein crystallization facility for high-throughput low volume crystallization and with imaging robotics. For example, we have the capability to screen 96 different crystallization conditions with as little as 15 microL of protein sample using a Mosquito liquid handling robot, or 1 microL of protein sample using free interface diffusion techniques.

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Low volume high-throughput custom protein crystallization services

SARomics Biostructures runs a state-of-the art Cassiopeia protein crystallization facility for high-throughput low volume crystallization and with imaging robotics. For example, we have the capability to screen 96 different crystallization conditions with as little as 15 microL of protein sample using a Mosquito liquid handling robot, or 1 microL of protein sample using free interface diffusion techniques.

Instant access to Synchrotron beamlines
SARomics Biostructures is conveniently located at the MAX-lab synchrotron in Lund and enjoys fast access to the Cassiopeia data collection facilities there. We can choose between three beamlines, each with a specific, purpose oriented design. This assures high quality X-ray data with no need to FedEx your crystals to remote synchrotrons!


Example of a ligand built into a high resolution electron density
Protein Crystallization Services, Crystallography and Drug Design:: SARomics Biostructures AB • P.O. Box 724 • SE-220 07 Lund • Sweden • Tel.+46 46 191276 • © 2012 •